ARAVA 20MG (30 TABLETS)

769911062

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Leflunomide 20mg

$64.00

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Brand Generic Brand

Product ID 8699809090477
Product Arava 20mg
Strength 20mg
Pack Size 30
Pharmaceutical Form Tablets
Active Ingredients Leflunomide
Manufacturer Aventis Pharmaceuticals
License Holder Sanofi Aventis
E.Q.US.Brand Name Arava
Origin France
Active-Passive-Not Avaliable Active

IMPORTANT WARNING:

Do not take leflunomide if you are pregnant or plan to become pregnant. Leflunomide may harm the fetus. You should not begin taking leflunomide until you have taken a pregnancy test with negative results and your doctor tells you that you are not pregnant. You must use an effective method of birth control before you begin taking leflunomide, during your treatment with leflunomide, and for 2 years after treatment. If your period is late or you miss a period during treatment with leflunomide, call your doctor immediately. Talk to your doctor if you plan to become pregnant within 2 years after stopping treatment with leflunomide. Your doctor can prescribe a treatment that will help to remove this medication more quickly from your body .

Leflunomide may cause liver damage that can be life-threatening and even cause death. The risk for liver damage is greatest in people taking other medications known to cause liver damage, and in people who already have liver disease. Tell your doctor if you have or have ever had hepatitis or any other type of liver disease and if you if you drink or have ever drunk large amounts of alcohol. Tell your doctor and pharmacist if you are taking acetaminophen (Tylenol, in other over-the-counter products), aspirin and other nonsteroidal anti-inflammatory medications (NSAIDs such as ibuprofen [Advil, Motrin] and naproxen [Aleve, Naprosyn], cholesterol-lowering medications (statins), etanercept (Enbrel), hydroxychloroquine, iron products, isoniazid (INH, Nydrazid, in Rifamate), methotrexate (Rheumatrex), niacin (nicotinic acid), or rifampin (Rifadin, Rimactane, in Rifamate, in Rifater). If you experience any of the following symptoms, call your doctor immediately: nausea, extreme tiredness, unusual bleeding or bruising, lack of energy, loss of appetite, pain in the upper right part of the stomach, yellowing of the skin or eyes, dark-colored urine, or flu-like symptoms.

Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests to check your body's response to leflunomide.

Talk to your doctor about the risks of taking leflunomide.

Why is this medication prescribed?

Leflunomide is used alone or in combination with other medications to treat rheumatoid arthritis (a condition in which the body attacks its own joints, causing pain, swelling, and loss of function). Leflunomide is in a class of medications called disease-modifying antirheumatic drugs (DMARDs). It works by decreasing inflammation and slowing the progress of the condition, which can help improve the physical activity of people with rheumatoid arthritis.

How should this medicine be used?

Leflunomide comes as a tablet to take by mouth. It is usually taken once a day. Your doctor may tell you to take a larger dose of leflunomide for the first 3 days of treatment. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take leflunomide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor may need to decrease your dose or stop treatment if you experience certain severe side effects. Be sure to tell your doctor how you are feeling during your treatment.

Leflunomide may help control the symptoms of your rheumatoid arthritis but does not cure it. Continue to take leflunomide even if you feel well. Do not stop taking leflunomide without talking to your doctor.

Other uses for this medicine

 

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

 

Before taking leflunomide,

  • tell your doctor      and pharmacist if you are allergic to leflunomide, any other medications,      or any of the ingredients in leflunomide tablets. Ask your pharmacist for      a list of the ingredients.
  • tell your doctor      and pharmacist what other prescription and nonprescription medications,      vitamins, nutritional supplements, and herbal products you are taking or      plan to take. Be sure to mention the medications listed in the IMPORTANT      WARNING section and any of the following: anticoagulants ('blood      thinners') such as warfarin (Coumadin); cholestyramine (Prevalite,      Questran); colestipol (Colestid); gold compounds such as auranofin      (Ridaura) and aurothioglucose (Aurolate, Solganol); medications to treat      cancer; other medications that suppress the immune system such as      azathioprine (Imuran), cyclosporine (Neoral, Sandimmune), sirolimus      (Rapamune), and tacrolimus (Prograf); Your doctor may need to change the      doses of your medications or monitor you carefully for side effects.
  • tell your doctor      if you have or have ever had serious infections or if you frequently get      infections, cancer or other conditions affecting the bone marrow or the      immune system (including human immunodeficiency virus [HIV] and acquired      immunodeficiency syndrome [AIDS]), or kidney disease.
  • tell your doctor      if you are breast-feeding.
  • if you are      planning to father a child, you should talk to your doctor about stopping      leflunomide and receiving a treatment to help to remove this medication      from your body more quickly.
  • ask your doctor      about the safe use of alcoholic beverages while you are taking      leflunomide.
  • Taking      leflunomide may decrease your ability to fight infection. Tell your doctor      if you have an infection now or if you have any signs of infection such as      fever, cough, or flu-like symptoms. If you experience any of the following      symptoms during your treatment with leflunomide, call your doctor: fever;      sore throat; cough; flu-like symptoms; area of warm, red, swollen, or      painful skin; painful, difficult, or frequent urination; or other signs of      infection. Your treatment with leflunomide may need to be interrupted if      you have an infection.
  • You may already      be infected with tuberculosis (TB; a serious lung infection) but not have      any symptoms of the disease. In this case, leflunomide may make your      infection more serious and cause you to develop symptoms. Tell your doctor      if you have or have ever had TB, if you have lived in or visited a country      where TB is common, or if you have been around someone who has or has ever      had TB. Before you begin your treatment with leflunomide, your doctor will      perform a skin test to see if you have TB. If you do have TB, your doctor      will treat this infection with antibiotics before you begin taking      leflunomide.
  • do not have any      vaccinations without talking to your doctor.
  • you should know      that leflunomide may cause high blood pressure. You should have your blood      pressure checked before starting treatment and regularly while you are      taking this medication.

What should I do if I forget a dose?

 

Take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

 

Leflunomide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • diarrhea
  • vomiting
  • heartburn
  • headache
  • dizziness
  • weight loss
  • back pain
  • muscle pain or weakness
  • pain, burning, numbness, or tingling in the hands      or feet
  • hair loss
  • mouth sores

Some side effects can be serious. If you experience any of the following symptoms or those listed in the IMPORTANT WARNING or SPECIAL PRECAUTIONS section, call your doctor immediately:

  • hives
  • rash
  • difficulty breathing
  • new or worsening cough
  • chest pain
  • blisters or peeling of skin
  • pale skin

Receiving medications which suppress the immune system may increase the risk of developing certain types of cancer. An increase in cancers was not reported in clinical studies with leflunomide to date. Talk to your doctor about the risks of receiving leflunomide.

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